Invitrogen

Desmoglein 2 (DSG2) Polyclonal Antibody

产品信息

PA5-121232

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

4.96 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2914804

产品详细信息

Positive test controls include: HepG2, HeLa, SW620, DU145, K-562. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.

Immunogen sequence: CHCGKGAKGF TPIPGTIEML HPWNNEGAPP EDKVVPSFLP VDQGGSLVGR NGVGGMAKEA TMKGSSSASI VKGQHEMSEM DGRWEEHRSL LSGRATQFTG ATGAIMTTET TKTARATGAS RDMAGAQAAA VALNEEFLRN YFTDKAASYT EEDENHTAKD CLLVYSQEET ESLNASIGCC SFIEGELDDR FLDDLGLKFK TLAEVCLGQK IDINKEIEQR QKPATETSMN TASHSLCEQT MVNSENTYSS GSSFPVPKSL QEANAEKVTQ EIVTERSVSS RQAQKVATPL PDPMASRNVI A

靶标信息

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。