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Antibody detects endogenous levels of total DSG4.
Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin family member 13; Desmoglein-4; Desmoglein4; lanceolate hair
基因别名: CDGF13; CDHF13; DSG4; HYPT6; LAH
UniProt ID: (Human) Q86SJ6, (Mouse) Q7TMD7, (Rat) Q6W3B0
Entrez Gene ID: (Human) 147409, (Mouse) 16769, (Rat) 291754