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The calculated molecular weight of EEF1D is 31 kDa, but the modified protein is about 35-40 kDa.
Immunogen sequence: SHRPGPRSG LSVSSLRPNR KMATNFLAHE KIWFDKFKYD DAERRFYEQM NGPVAGASRQ ENGASVILRD IARARENIQK SLAGSSGPGA SSGTSGDHGE LVVRIASLEV ENQSLRGVVQ ELQQAISKLE ARLNVLEKSS PGHRATAPQT QHVSPMRQVE PPAKKPATPA EDDEDDDIDL FGSDNEEEDK EAAQLREERL RQYAEKKAKK PALVAKSSIL LDVKPWDDET DMAQLEACVR SIQLDGLVWG ASKLVPVGYG IRKLQIQCVV EDDKVGTDLL EEEITKFEEH VQSVDIAAFN KI (347-647 aa encoded by BC007847)
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Antigen NY-CO-4; EEF 1D; EF 1 delta; EF 1D; EF-1-delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); guanine nucleotide exchange protein; translation elongation factor 1-delta subunit
基因别名: EEF1D; EF-1-delta; EF-1D; EF1D; FP1047
UniProt ID: (Human) P29692, (Mouse) P57776, (Rat) Q68FR9
Entrez Gene ID: (Human) 1936, (Mouse) 66656, (Rat) 300033
分子生物学功能: translation elongation factor