Product References
Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells.
Current biology : CB
Aguilar-Cuenca R,Llorente-González C,Chapman JR,Talayero VC,Garrido-Casado M,Delgado-Arévalo C,Millán-Salanova M,Shabanowitz J,Hunt DF,Sellers JR,Heissler SM,Vicente-Manzanares M
AHR5072 was used in Western blot to study amino acid Tyr (Y) 155, of the regulatory light chain, as a novel regulatory site that spatially controls active non-muscle myosin II function in vivo.
Mon Jul 06 00:00:00 EDT 2020
Direct visualization of single-molecule membrane protein interactions in living cells.
PLoS biology
Kim DH,Park S,Kim DK,Jeong MG,Noh J,Kwon Y,Zhou K,Lee NK,Ryu SH
AHR5072 was used in Immunocytochemistry-immunoflourescence to develop a co-immunoimmobilisation assay enabling the direct observation of membrane protein interactions in single living cells that overcomes the limitations of currently prevalent proximity-based indirect methods.
Sat Dec 01 00:00:00 EST 2018
High CD90 (THY-1) expression positively correlates with cell transformation and worse prognosis in basal-like breast cancer tumors.
PloS one
Lobba ARM,Carreira ACO,Cerqueira OLD,Fujita A,DeOcesano-Pereira C,Osorio CAB,Soares FA,Rameshwar P,Sogayar MC
AHR5072 was used in Immunocytochemistry-immunoflourescence to investigate the functional role of CD90 expression and to assess its oncogenic nature in human mammary cells.
Tue Apr 16 00:00:00 EDT 2019
Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis.
Traffic (Copenhagen, Denmark)
Elkin SR,Oswald NW,Reed DK,Mettlen M,MacMillan JB,Schmid SL
AHR5072 was used in blocking or activating experiment to propose that ikarugamycin is a useful reagent to study routes of endocytic trafficking
Sat Oct 01 00:00:00 EDT 2016
EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging.
Clinical and translational gastroenterology
Zhou J,Joshi BP,Duan X,Pant A,Qiu Z,Kuick R,Owens SR,Wang TD
AHR5072 was used in immunocytochemistry to discuss detection of colorectal cancer using conventional wide-field endoscopy.
Thu Jul 16 00:00:00 EDT 2015
Differential effects of EGFR ligands on endocytic sorting of the receptor.
Traffic (Copenhagen, Denmark)
Roepstorff K,Grandal MV,Henriksen L,Knudsen SL,Lerdrup M,Grøvdal L,Willumsen BM,van Deurs B
AHR5072 was used in immunocytochemistry, immunoprecipitation, and western blot to investigate the effect of EGFR ligands on receptor internalization and endocytic sorting
Sat Aug 01 00:00:00 EDT 2009
Sulindac metabolites inhibit epidermal growth factor receptor activation and expression.
Journal of carcinogenesis
Pangburn HA,Kraus H,Ahnen DJ,Rice PL
AHR5072 was used in western blot to test if sulindac metabolites block activation or expression of the epidermal growth factor receptor
Fri Sep 02 00:00:00 EDT 2005
Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor.
The American journal of pathology
Shen X,Kramer RH
AHR5072 was used in western blot to investigate factors that protect malignant cells from detachment-induced death
Fri Oct 01 00:00:00 EDT 2004