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产品信息
11165-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EIF3G Fusion Protein Ag1653 (1-320 aa encoded by BC000733)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MPTGDFDSK PSWADQVEEE GEDDKCVTSE LLKGIPLATG DTSPEPELLP GAPLPPPKEV INGNIKTVTE YKIDEDGKKF KIVRTFRIET RKASKAVARR KNWKKFGNSE FDPPGPNVAT TTVSDDVSMT FITSKEDLNC QEEEDPMNKL KGQKIVSCRI CKGDHWTTRC PYKDTLGPMQ KELAEQLGLS TGEKEKLPGE LEPVQATQNK TGKYVPPSLR DGASRRGESM QPNRRADDNA TIRVTNLSED TRETDLQELF RPFGSISRIY LAKDKTTGQS KGFAFISFHR REDAARAIAG VSGFGYDHLI LNVEWAKPST N (1-320 aa encoded by BC000733)
靶标信息
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: eIF-3 RNA-binding subunit; eIF-3-delta; eIF3 p42; eIF3 p44; eIF3g; Eukaryotic translation initiation factor 3 RNA-binding subunit; Eukaryotic translation initiation factor 3 subunit 4; Eukaryotic translation initiation factor 3 subunit G
基因别名: eIF3-delta; EIF3-P42; eIF3-p44; EIF3G; EIF3S4
UniProt ID: (Human) O75821
Entrez Gene ID: (Human) 8666
