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Immunogen sequence: MAASAKKKN KKGKTISLTD FLAEDGGTGG GSTYVSKPVS WADETDDLEG DVSTTWHSND DDVYRAPPID RSILPTAPRA AREPNIDRSR LPKSPPYTAF LGNLPYDVTE ESIKEFFRGL NISAVRLPRE PSNPERLKGF GYAEFEDLDS LLSALSLNEE SLGNRRIRVD VADQAQDKDR DDRSFGRDRN RDSDKTDTDW RARPATDSFD DYPPRRGDDS FGDKYRDRYD SDRYRDGYRD GYRDGPRRDM DRYGGRDRYD DRGSRDYDRG YDSRIGSGRR AFGSGYRRDD DYRGGGDRYE DRYDRRDDRS WSSRDDYSRD DYRRDDRGPP QRPKLNLKPR STPKEDDSSA S (1-350 aa encoded by BC073154)
The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609
基因别名: 2310046H11Rik; AL024095; C85189; EIF-4B; Eif4a2; EIF4B; PRO1843
UniProt ID: (Human) P23588, (Mouse) Q8BGD9
Entrez Gene ID: (Human) 1975, (Rat) 300253, (Mouse) 75705