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产品信息
PA5-61061
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640980
产品详细信息
Immunogen sequence: LFVHPLWNRS CVACGNDIAL IKLSRSAQLG DAVQLASL
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.
靶标信息
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
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生物信息学
蛋白别名: Chymotrypsin-like elastase family member 3A; chymotrypsin-like elastase family, member 3A; elastase 1; elastase 3A, pancreatic; Elastase IIIA; Elastase-3A; Protease E
基因别名: CELA3A; ELA3; ELA3A
UniProt ID: (Human) P09093
Entrez Gene ID: (Human) 10136
