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Immunogen sequence: MVMIISTMEP QVSNGPTSNT SNGPSSNNRN CPSPMQTGAT TDDSKTNLIV NYLPQNMTQE EFRSLFGSIG EIESCKLVRD KITGQSLGYG FVNYIDPKDA EKAINTLNGL RLQTKTIKVS YARPSSASIR DANLYVSGLP KTMTQKELEQ LFSQYGRIIT SRILVGQVTG VSRGVGFIRF DKRIEAEEAI KGLNGQKPSG ATEPITVKFA NNPSQKSSQA LLSQLYQSPN RRYPGPLHHQ AQRFRLDNLL NMAYGVKRFS PITIDGMTSL VGMNIPGHTG TGWCIFVYNL SPDSDESVLW QLFGPFGAVN NVKVIRDFNT NKCKGFGFVT MTNYDEAAMA ITSLNGYRLG DRVLQVSFKT NKAHKS
HuD, otherwise known as ELAV-like protein 4 or PNEM, is a protein that in humans is encoded by the ELAVL4 gene. This human gene is located at 1p34 by in situ hybridization. The HuD/ELAVL4 protein is an RNA-binding protein. ELAVL4 has specificity for 3-prime uridylate-rich untranslated regions of growth factor mRNAs. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the, half-life of the transcript is increased. Additionally, HuD is important in neurons during brain development and plasticity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV-like protein 4; Hu antigen D; HU-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD; RNA-binding protein HUD3
基因别名: Elav; ELAVL4; HUD; PNEM; r-HuD; RGD1561943
UniProt ID: (Human) P26378, (Mouse) Q61701, (Rat) O09032
Entrez Gene ID: (Rabbit) 100359216, (Human) 1996, (Mouse) 15572, (Rat) 432358