Invitrogen

EMX1 Polyclonal Antibody

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EMX1 Antibody (PA5-35373) in WB

Western blot analysis of EMX1 in various lysates. Samples were incubated with EMX1 polyclonal antibody (Product # PA5-35373) using a dilution of 1:1,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: MDA-MB-231 whole cell lysate; Lane 2: HepG2 whole cell lysate; Lane 3: Jurkat whole cell lysate; Lane 4: Mouse brain tissue lysate. Predicted band size: 28 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

EMX1 Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-35373

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化 (IHC)

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免疫组织化学（多聚甲醛固定） (IHC (PFA))

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免疫组化（冰冻） (IHC (F))

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免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 228-257 amino acids from the C-terminal region of human EMX1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2552683

靶标信息

EMX1 is a transcription factor, which in cooperation with EMX2. It acts to generate the boundary between the roof and archipallium in the developing brain. It may function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP.

Molecular brain

Wiebe S,Huang Z,Ladak RJ,Skalecka A,Cagnetta R,Lacaille JC,Aguilar-Valles A,Sonenberg N

PA5-35373 was used in Immunohistochemistry (Frozen) to indicate that translational control by 4EHP and mTORC1 in both excitatory and inhibitory neurons are necessary for working memory.

Wed Jan 18 00:00:00 EST 2023

The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior.

Molecular autism

Wiebe S,Meng XQ,Kim SH,Zhang X,Lacaille JC,Aguilar-Valles A,Sonenberg N

Published figure using EMX1 polyclonal antibody (Product # PA5-35373) in Immunohistochemistry

Mon Nov 23 00:00:00 EST 2020

The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior.

Molecular autism

Wiebe S,Meng XQ,Kim SH,Zhang X,Lacaille JC,Aguilar-Valles A,Sonenberg N

Published figure using EMX1 polyclonal antibody (Product # PA5-35373) in Immunohistochemistry

Mon Nov 23 00:00:00 EST 2020

16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development.

eLife

Roth JG,Muench KL,Asokan A,Mallett VM,Gai H,Verma Y,Weber S,Charlton C,Fowler JL,Loh KM,Dolmetsch RE,Palmer TD

PA5-35373 was used in Immunocytochemistry-immunoflourescence to reveal disruptions in gene programs related to both nervous system function and cellular metabolism.

Tue Nov 10 00:00:00 EST 2020

WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.

EMBO reports

Kim YJ,Osborn DP,Lee JY,Araki M,Araki K,Mohun T,Känsäkoski J,Brandstack N,Kim HT,Miralles F,Kim CH,Brown NA,Kim HG,Martinez-Barbera JP,Ataliotis P,Raivio T,Layman LC,Kim SH

PA5-35373 was used in Western Blot to reveal a novel class of ciliopathy caused by WDR11 mutations and suggests that CHH/KS may be a part of the human ciliopathy spectrum.