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产品信息
MA1-35363
产品规格
种属反应
Human
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
LMR-42
抗原
Proprietary immunogen
偶联物
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
保存液
tissue culture supernatant with 0.7% BSA
内含物
0.1% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2172429
产品详细信息
LMR-42 detects an outer-surface epitope of a 55 kDa plasma membrane protein overexpressed in several human non-Pgpmultidrug-resistant (MDR) tumor cell lines. Expression cloning revealed that the LMR-42 antigen is identical to the human endothelial cell protein Creceptor (EPCR). Protein C is the zymogen of the key anticoagulant enzyme, activated protein C (APC).
靶标信息
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activated protein C receptor; APC receptor; bA42O4.2; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Endothelial cell protein C receptor; Endothelial protein C receptor; protein C receptor, endothelial
基因别名: CCCA; CCD41; EPCR; PROCR
UniProt ID: (Human) Q9UNN8
Entrez Gene ID: (Human) 10544
