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产品信息
24452-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EPHA6 Fusion Protein Ag19871 (896-1036 aa encoded by BC156733)
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PAPMGCPAS LHQLMLHCWQ KERNHRPKFT DIVSFLDKLI RNPSALHTLV EDILVMPESP GEVPEYPLFV TVGDWLDSIK MGQYKNNFVA AGFTTFDLIS RMSIDDIRRI GVILIGHQRR IVSSIQTLRL HMMHIQEKGF HV (896-1036 aa encoded by BC156733)
靶标信息
EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp434C1418; EHK-2; EK12; EPH homology kinase 2; EPH-like kinase 12; ephrin receptor EphA6; Ephrin type-A receptor 6; FLJ35246
基因别名: EHK-2; EHK2; EK12; EPA6; EPHA6; HEK12; PRO57066
UniProt ID: (Human) Q9UF33
Entrez Gene ID: (Human) 285220
