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ERLIN1 Antibody (TA809148) in IHC (P)
Immunohistochemical staining of paraffin-embedded human lymph node tissue within the normal limits using anti-ERLIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809148)(1:2000).
产品信息
TA809148
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI4B1
抗原
Human recombinant protein fragment corresponding to amino acids 107-346 of human ERLIN1 produced in E.coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; Endoplasmic reticulum lipid raft-associated protein 1; Erlin-1; OTTHUMP00000059425; OTTHUMP00000197867; Protein KE04; SPFH domain family, member 1; SPFH domain-containing protein 1; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
基因别名: C10orf69; Erlin-1; ERLIN1; KE04; KEO4; SPFH1; SPG62
UniProt ID: (Human) O75477
Entrez Gene ID: (Human) 10613
