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PA3-011 detects ERp29 protein in rat, mouse, hamster, canine, human, non-human primate, bovine and guinea pig samples.
PA3-011 has successfully been used in immunofluorescence, immunoprecipitation and Western blot procedures. By Western blot, this antibody detects an ~29 kDa protein representing ERp29 in rat liver homogenate. Immunofluorescence data demonstrates that ERp29 is localized to the ER of rat thyrocytes using PA3-011.
The PA3-011 immunogen was a 6-histidine epitope tagged full length recombinant ERp29 protein.
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: endoplasmic reticulum lumenal protein ERp28; endoplasmic reticulum protein 29; Endoplasmic reticulum protein ERp29; Endoplasmic reticulum resident protein 28; Endoplasmic reticulum resident protein 29; Endoplasmic reticulum resident protein 31; endoplasmic retuclum protein 29; epididymis secretory protein Li 107; ERp28; ERp29; ERp31; protein disulfide isomerase family A, member 9
基因别名: 1200015M03Rik; 2810446M09Rik; AW209030; C12orf8; ERP28; ERP29; ERp31; HEL-S-107; PDI-DB; PDIA9
UniProt ID: (Bovine) P81623, (Human) P30040, (Rat) P52555, (Mouse) P57759
Entrez Gene ID: (Bovine) 613357, (Dog) 477482, (Human) 10961, (Chinese hamster) 100762501, (Guinea pig) 100731699, (Rat) 117030, (Mouse) 67397
分子生物学功能: membrane traffic protein