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Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (Met1-Ala248) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2310008D05Rik; Endothelial cell-selective adhesion molecule; HUEL (C4orf1)-interacting protein; LP4791 protein
基因别名: ESAM; UNQ220/PRO246; W117m
UniProt ID: (Human) Q96AP7
Entrez Gene ID: (Human) 90952