Invitrogen

ETFDH Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他5个ETFDH抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (3)
高级验证 (1)

ETFDH Antibody in Immunohistochemistry (IHC)

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ETFDH Antibody (PA5-59808) in IHC

Immunohistochemical staining of ETFDH in human duodenum and pancreas tissues using ETFDH Polyclonal Antibody (Product # PA5-59808). Corresponding ETFDH RNA-seq data are presented for the same tissues.

Product Image Gallery

ETFDH Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of ETFDH demonstrates antibody specificity. Immunohistochemical analysis of ETFDH using anti-ETFDH Polyclonal Antibody (Product # PA5-59808), shows significant staining of ETFDH in human duodenum and shows minimal or weak staining in human pancreas tissues. The relative expression levels of ETFDH within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-59808

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human ETFDH. Recombinant protein control fragment (Product #RP-96739).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2641134

产品详细信息

Immunogen sequence: LAVAHEKDIR VCLVEKAAQI GAHTLSGACL DPGAFKELFP DWKEKGAPLN TPVTEDRFGI LTEKYRIPVP ILPGLPMN

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.

靶标信息

Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase

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基因别名: ETFDH; ETFQO; MADD

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UniProt ID: (Human) Q16134

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Entrez Gene ID: (Human) 2110

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功能

electron-transferring-flavoprotein dehydrogenase activity electron carrier activity oxidoreductase activity oxidoreductase activity, oxidizing metal ions with flavin as acceptor metal ion binding quinone binding ubiquinone binding flavin adenine dinucleotide binding 4 iron, 4 sulfur cluster binding oxidoreductase

参与通路

response to oxidative stress electron transport chain respiratory electron transport chain fatty acid beta-oxidation using acyl-CoA dehydrogenase