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产品信息
12280-1-AP
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ETS2 Fusion Protein Ag2929 (84-444 aa encoded by BC017040)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: KATFSGFKK EQRRLGIPKN PWLWSEQQVC QWLLWATNEF SLVNVNLQRF GMNGQMLCNL GKERFLELAP DFVGDILWEH LEQMIKENQE KTEDQYEENS HLTSVPHWIN SNTLGFGTEQ APYGMQTQNY PKGGLLDSMC PASTPSVLSS EQEFQMFPKS RLSSVSVTYC SVSQDFPGSN LNLLTNNSGT PKDHDSPENG ADSFESSDSL LQSWNSQSSL LDVQRVPSFE SFEDDCSQSL CLNKPTMSFK DYIQERSDPV EQGKPVIPAA VLAGFTGSGP IQLWQFLLEL LSDKSCQSFI SWTGDGWEFK LADPDEVARR WGKRKNKPKM NYEKLSRGLR YYYDKNIIHK TSGKRYVYRF VC (84-444 aa encoded by BC017040)
靶标信息
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: oncogene ETS-2; Protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2
基因别名: AU022856; Ets-2; ETS2; ETS2IT1
UniProt ID: (Human) A6NM68, (Mouse) P15037
Entrez Gene ID: (Human) 2114, (Mouse) 23872
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
glucocorticoid receptor binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
ectodermal cell fate commitment
transcription, DNA-templated
mesoderm development
cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
primitive streak formation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
