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ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: oncogene ETS-2; Protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2
基因别名: AU022856; Ets-2; ETS2; ETS2IT1
UniProt ID: (Human) A6NM68, (Mouse) P15037
Entrez Gene ID: (Human) 2114, (Mouse) 23872