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Antibody is stable for 24 months.
Positive Control: MCF-7 cells. Tonsil. Cellular Localization: Cytoplasmic, granular
Specificity Comments: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
EPX belongs to the peroxidase family, XPO subfamily. Defects in EPX are the cause of eosinophil peroxidase deficiency (EPD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Eosinophil peroxidase; EPO; EPX PEN; PERE
基因别名: EPER; EPO; EPP; EPX; EPX-PEN; EPXD
UniProt ID: (Human) P11678
Entrez Gene ID: (Human) 8288
分子生物学功能:
peroxidase