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产品信息
PA1-22484
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment, corresponding to amino acids 1-74 of mature Human Eotaxin.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_558793
产品详细信息
PA1-22484 detects Eotaxin in Human samples. Does not react with mouse samples.
靶标信息
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine 11; chemokine (C-C motif) ligand 11; Eosinophil chemotactic protein; Eotaxin; Eotaxin 1; eotaxin-1; Eotaxin1; MGC22554; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); Small-inducible cytokine A11
基因别名: CCL11; SCYA11
UniProt ID: (Human) P51671
Entrez Gene ID: (Human) 6356
positive regulation of endothelial cell proliferation
chronic inflammatory response
monocyte chemotaxis
mast cell chemotaxis
protein phosphorylation
cellular calcium ion homeostasis
chemotaxis
inflammatory response
cytoskeleton organization
actin filament organization
cell adhesion
signal transduction
G-protein coupled receptor signaling pathway
regulation of cell shape
response to radiation
response to virus
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of actin filament polymerization
response to interleukin-13
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
branching involved in mammary gland duct morphogenesis
mammary duct terminal end bud growth
chemokine-mediated signaling pathway
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-4
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
