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EphA6 Antibody (PA5-115187) in IHC (P)
Immunohistochemistry analysis of EphA6 in rat spleen tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115187) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.
产品信息
PA5-115187
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human EPHA6(Accession Q9UF33), corresponding to amino acid residues S953-R1003.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899823
产品详细信息
Antibody detects endogenous levels of total EPHA6.
靶标信息
EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp434C1418; EHK-2; EK12; EPH homology kinase 2; Eph receptor A6; EPH-like kinase 12; ephrin receptor EphA6; Ephrin type-A receptor 6; FLJ35246; tyrosine-protein kinase receptor EHK-2
基因别名: EHK-2; EHK2; EK12; EPA6; EPHA6; HEK12; m-ehk2; PRO57066
UniProt ID: (Human) Q9UF33
Entrez Gene ID: (Human) 285220, (Rat) 29202, (Mouse) 13840
molecular_function
ephrin receptor activity
ATP binding
protein kinase activity
nucleotide binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
