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EphB3 Antibody (MA5-37867) in WB
Western blot analysis of EphB3 in extracts of various cell lines. Samples were incubated with EphB3 Monoclonal antibody (Product # MA5-37867) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
MA5-37867
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC2384
抗原
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Eph receptor B3 (EPHB3) (EPHB3) (P54753)
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897787
产品详细信息
Positive Samples: HeLa, HT-29, SH-SY5Y, Mouse brain, Rat brain
Immunogen sequence: SELAWTSHPE SGWEEVSGYD EAMNPIRTYQ VCNVRESSQN NWLRTGFIWR RDVQRVYVEL KFTVRDCNSI PNIPGSCKET FNLFYYEADS DVASASSPFW M
靶标信息
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Developmental kinase 5; EK2; Embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; Ephrin type-B receptor 3; human embryo kinase 2; mDK-5; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO6
基因别名: AW456895; Cek10; EK2; EPHB3; ETK2; HEK2; MDK5; Sek4; TYRO6
UniProt ID: (Human) P54753, (Mouse) P54754
Entrez Gene ID: (Human) 2049, (Mouse) 13845, (Rat) 287989
ephrin receptor activity
ATP binding
axon guidance receptor activity
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane-ephrin receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
angiogenesis
urogenital system development
axon guidance
axonal fasciculation
cell migration
peptidyl-tyrosine phosphorylation
central nervous system projection neuron axonogenesis
corpus callosum development
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
substrate adhesion-dependent cell spreading
regulation of GTPase activity
protein autophosphorylation
ephrin receptor signaling pathway
thymus development
digestive tract morphogenesis
regulation of axonogenesis
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
phosphorylation
