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Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (96%), Rat (97%), Chicken (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EPS-15-interacting protein 2; Eps15 binding protein; Epsin-2
基因别名: EHB21; EPN2; KIAA1065
UniProt ID: (Human) Q52LD0
Entrez Gene ID: (Human) 22905