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产品信息
MA1-7277
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG2
分类
Monoclonal
类型
Antibody
克隆号
H11B
抗原
EBV EA-D.
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.1% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1017106
产品详细信息
The MA1-7277 antibody reacts with Epstein-Barr virus EA-D in viral and infected tissue samples.
MA1-7277 has been successfully used in Western blot, Immunofluorescence and Immunohistochemical applications.
The MA1-7277 antibody was raised against EBV EA-D protein.
靶标信息
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EBV; EBV EA; EBV EAD; EBV early
