Product References
MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells.
Cell reports
Jeong J,Shin JH,Li W,Hong JY,Lim J,Hwang JY,Chung JJ,Yan Q,Liu Y,Choi J,Wysolmerski J
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA1-35720) in Immunocytochemistry
Tue Dec 28 00:00:00 UTC 2021
MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells.
Cell reports
Jeong J,Shin JH,Li W,Hong JY,Lim J,Hwang JY,Chung JJ,Yan Q,Liu Y,Choi J,Wysolmerski J
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA1-35720) in Immunocytochemistry
Tue Dec 28 00:00:00 UTC 2021
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers.
Cancer discovery
Li BT,Michelini F,Misale S,Cocco E,Baldino L,Cai Y,Shifman S,Tu HY,Myers ML,Xu C,Mattar M,Khodos I,Little M,Qeriqi B,Weitsman G,Wilhem CJ,Lalani AS,Diala I,Freedman RA,Lin NU,Solit DB,Berger MF,Barber PR,Ng T,Offin M,Isbell JM,Jones DR,Yu HA,Thyparambil S,Liao WL,Bhalkikar A,Cecchi F,Hyman DM,Lewis JS,Buonocore DJ,Ho AL,Makker V,Reis-Filho JS,Razavi P,Arcila ME,Kris MG,Poirier JT,Shen R,Tsurutani J,Ulaner GA,de Stanchina E,Rosen N,Rudin CM,Scaltriti M
MA1-35720 was used in Western Blotting to address unmet needs of patients with HER2-activated tumors and no approved targeted therapy.
Fri May 01 00:00:00 UTC 2020
Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity through Redistribution of Phosphorylated Caveolin-1.
Molecular cancer research : MCR
Indira Chandran V,Månsson AS,Barbachowska M,Cerezo-Magaña M,Nodin B,Joshi B,Koppada N,Saad OM,Gluz O,Isaksson K,Borgquist S,Jirström K,Nabi IR,Jernström H,Belting M
MA1-35720 was used in Cell Culture to identify hypoxic regulation of caveolin-1 as a resistance mechanism to T-DM1 with potential implications for individualized treatment of breast cancer.
Wed Apr 01 00:00:00 UTC 2020
Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells.
The Journal of biological chemistry
Jeong J,Choi J,Kim W,Dann P,Takyar F,Gefter JV,Friedman PA,Wysolmerski JJ
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA1-35720) in Immunofluorescence
Fri Jan 18 00:00:00 UTC 2019
HER2 signaling regulates HER2 localization and membrane retention.
PloS one
Jeong J,Kim W,Kim LK,VanHouten J,Wysolmerski JJ
MA135720 was used in immunocytochemistry and western blot to explore how HER2 signaling contributes to the formation and maintenance of membrane protrusions
Wed Aug 30 00:00:00 UTC 2017
HER2 signaling regulates HER2 localization and membrane retention.
PloS one
Jeong J,Kim W,Kim LK,VanHouten J,Wysolmerski JJ
MA135720 was used in immunocytochemistry and western blot to explore how HER2 signaling contributes to the formation and maintenance of membrane protrusions
Wed Aug 30 00:00:00 UTC 2017
The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.
The Journal of biological chemistry
Jeong J,VanHouten JN,Kim W,Dann P,Sullivan C,Choi J,Sneddon WB,Friedman PA,Wysolmerski JJ
MA135720 was used in immunocytochemistry, immunohistochemistry, immunoprecipitation, and western blot to show that NHERF1 and PMCA2 modulate HER2 signaling and membrane retention in breast cancers
Fri Apr 21 00:00:00 UTC 2017
The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.
The Journal of biological chemistry
Jeong J,VanHouten JN,Kim W,Dann P,Sullivan C,Choi J,Sneddon WB,Friedman PA,Wysolmerski JJ
MA135720 was used in immunocytochemistry, immunohistochemistry, immunoprecipitation, and western blot to show that NHERF1 and PMCA2 modulate HER2 signaling and membrane retention in breast cancers
Fri Apr 21 00:00:00 UTC 2017
PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Proceedings of the National Academy of Sciences of the United States of America
Jeong J,VanHouten JN,Dann P,Kim W,Sullivan C,Yu H,Liotta L,Espina V,Stern DF,Friedman PA,Wysolmerski JJ
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA1-35720) in Immunofluorescence
Tue Jan 19 00:00:00 UTC 2016
PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Proceedings of the National Academy of Sciences of the United States of America
Jeong J,VanHouten JN,Dann P,Kim W,Sullivan C,Yu H,Liotta L,Espina V,Stern DF,Friedman PA,Wysolmerski JJ
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA1-35720) in Immunofluorescence
Tue Jan 19 00:00:00 UTC 2016
PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Proceedings of the National Academy of Sciences of the United States of America
Jeong J,VanHouten JN,Dann P,Kim W,Sullivan C,Yu H,Liotta L,Espina V,Stern DF,Friedman PA,Wysolmerski JJ
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA1-35720) in Immunofluorescence
Tue Jan 19 00:00:00 UTC 2016
Fibroblastic reticular cell tumor of the breast: A case report and review of the literature.
Experimental and therapeutic medicine
Li H,Shen P,Liang Y,Zhang F
MA135720 was used in immunohistochemistry - paraffin section to characterize and present the first case of fibroblastic reticular cell tumor of the breast
Mon Feb 01 00:00:00 UTC 2016
Heat shock protein 27 and gross cystic disease fluid protein 15 play critical roles in molecular apocrine breast cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Liu X,Feng C,Liu J,Zhao L,Liu J,Zhang W,Liu N,Niu Y
MA1-35720 was used in immunohistochemistry to characterize human molecular apocrine breast cancer samples
Wed Jun 01 00:00:00 UTC 2016
St Gallen molecular subtypes in feline mammary carcinoma and paired metastases-disease progression and clinical implications from a 3-year follow-up study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Soares M,Correia J,Peleteiro MC,Ferreira F
MA135720 was used in immunohistochemistry to describe the clinical, pathological, and immunophenotypic features collected from 61 queens with feline mammary carcinoma
Tue Mar 01 00:00:00 UTC 2016
Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status.
Oncotarget
Soares M,Ribeiro R,Najmudin S,Gameiro A,Rodrigues R,Cardoso F,Ferreira F
MA135720 was used in immunohistochemistry - paraffin section to develop an assay to measure serum HER2 in order to diagnose cats with mammary carcinomas
Tue Apr 05 00:00:00 UTC 2016
Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes.
Cellular oncology (Dordrecht)
Papanikolaou V,Stefanou N,Dubos S,Papathanasiou I,Palianopoulou M,Valiakou V,Tsezou A
MA1-35720 was used in western blot to evaluate the role of leptin/STAT3 and HER2 receptor in tamoxifen resistance
Wed Apr 01 00:00:00 UTC 2015
Tissue biomarkers in prognostication of serous ovarian cancer following neoadjuvant chemotherapy.
BioMed research international
Khandakar B,Mathur SR,Kumar L,Kumar S,Datta Gupta S,Iyer VK,Kalaivani M
MA1-35720 was used in immunohistochemistry to attempt to identify prognostic biomarkers in serous ovarian cancer patients treated with neoadjuvant chemotherapy
Mon Jan 19 00:00:00 UTC 2015
Ki-67 as a predictor of response to neoadjuvant chemotherapy in breast cancer patients.
Journal of breast cancer
Kim KI,Lee KH,Kim TR,Chun YS,Lee TH,Park HK
MA1-35720 was used in immunohistochemistry to study the value of Ki67 expression in predicting the response of breast cancer patients to neoadjuvant chemotherapy
Sat Mar 01 00:00:00 UTC 2014
Primary acinic cell carcinoma of the breast: a case report and review of the literature.
International journal of surgical pathology
Zhao Y,Li W,Lang R,Yang Y,Gao X,Zheng Y,Zhang C,Fu X,Fu L
MA1-35720 was used in immunohistochemistry to report the case of primary acinic cell carcinoma of the breast in a 38-year-old woman.
Tue Apr 01 00:00:00 UTC 2014
Contrast enhanced computed tomography is indicative for angiogenesis pattern and display prognostic significance in breast cancer.
BMC cancer
Li J,Zhang Y,Zhang W,Gao Y,Jia S,Guo J
MA1-35720 was used in immunohistochemistry - paraffin section to use Contrast-enhanced computer technology to display prognostic significance in breast cancer
Mon Sep 15 00:00:00 UTC 2014
Assessment of Her-2/neu status using immunocytochemistry and fluorescence in situ hybridization on fine-needle aspiration cytology smears: experience from a tertiary care centre in India.
Diagnostic cytopathology
Durgapal P,Mathur SR,Kalamuddin M,Datta Gupta S,Parshad R,Julka PK,Panda SK
MA1-35720 was used in immunohistochemistry to assess the accuracy of breast cancer HER2 determinations made using immunohistochemical and FISH analysis of fine-needle aspiration cytology smears
Fri Aug 01 00:00:00 UTC 2014
Are breast cancer molecular classes predictive of survival in patients with long follow-up?
Disease markers
Pracella D,Bonin S,Barbazza R,Sapino A,Castellano I,Sulfaro S,Stanta G
MA1-35720 was used in immunohistochemistry to study the value of breast cancer molecular class in predicting long-term survival
Tue Jul 08 00:00:00 UTC 2014
Tumor-infiltrating lymphocytes, tumor characteristics, and recurrence in patients with early breast cancer.
American journal of clinical oncology
Kim ST,Jeong H,Woo OH,Seo JH,Kim A,Lee ES,Shin SW,Kim YH,Kim JS,Park KH
MA1-35720 was used in immunohistochemistry to study the relationships between tumor-infiltrating lymphocytes, breast cancer characteristics and tumor recurrence
Sat Jun 01 00:00:00 UTC 2013
MYC overexpression and poor prognosis in sporadic breast cancer with BRCA1 deficiency.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Ren J,Jin F,Yu Z,Zhao L,Wang L,Bai X,Zhao H,Yao W,Mi X,Wang E,Olopade OI,Wei M
MA1-35720 was used in immunohistochemistry (paraffin) to study BRAC1-deficiency in sporadic breast cancer.
Sun Dec 01 00:00:00 UTC 2013
An associated classification of triple negative breast cancer: the risk of relapse and the response to chemotherapy.
International journal of clinical and experimental pathology
Zhang J,Wang Y,Yin Q,Zhang W,Zhang T,Niu Y
MA1-35720 was used in immunohistochemistry (paraffin) to study triple negative breast cancer in Chinese women.
Fri Feb 07 00:00:00 UTC 2014
Prognostic and predictive significance of MYC and KRAS alterations in breast cancer from women treated with neoadjuvant chemotherapy.
PloS one
Pereira CB,Leal MF,de Souza CR,Montenegro RC,Rey JA,Carvalho AA,Assumpção PP,Khayat AS,Pinto GR,Demachki S,de Arruda Cardoso Smith M,Burbano RR
MA1-35720 was used in immunohistochemistry (paraffin) to investigate prognostic or predictive biomarkers of breast cancer.
Tue Sep 24 00:00:00 UTC 2013
Epithelial-mesenchymal transition in breast cancer correlates with high histological grade and triple-negative phenotype.
Histopathology
Jeong H,Ryu YJ,An J,Lee Y,Kim A
MA1-35720 was used in immunohistochemistry to study the correlation of epithelial-mesenchymal transition with triple negative phenotype and high histological grade in breast cancer
Tue May 01 00:00:00 UTC 2012
Investigation of immunohistochemical ERα, ERβ and ERβcx expressions in normal and neoplastic breast tissues.
Pathology, research and practice
Bozkurt KK,Kapucuoğlu N
MA1-35720 was used in immunohistochemistry to study the expression of ERalpha, ERbeta and ERbetacx in normal and neoplastic breast tissues
Thu Mar 15 00:00:00 UTC 2012
Plasma human mammaglobin mRNA associated with poor outcome in patients with breast cancer.
Genetics and molecular research : GMR
Lee GW,Kim JY,Koh EH,Kang D,Choi DS,Maeng KY,Lee JS
MA1-35720 was used in immunohistochemistry to study the prognostic value of plasma mammoglobin mRNA levels in breast cancer
Wed Nov 28 00:00:00 UTC 2012
Survivin regulation by HER2 through NF-κB and c-myc in irradiated breast cancer cells.
Journal of cellular and molecular medicine
Papanikolaou V,Iliopoulos D,Dimou I,Dubos S,Kappas C,Kitsiou-Tzeli S,Tsezou A
MA1-35720 was used in western blot to study the importance of survivin to HER2(+) breast cancer radioresistance
Fri Jul 01 00:00:00 UTC 2011
Immunohistochemical COX-2 overexpression correlates with HER-2/neu overexpression in invasive breast carcinomas: a pilot study.
Pathology, research and practice
Çiriş IM,Bozkurt KK,Başpinar S,Kapucuoğlu FN
MA1-35720 was used in immunohistochemistry to investigate the correlation of COX-2 overexpression with HER-2/neu overexpression in invasive breast carcinomas
Tue Mar 15 00:00:00 UTC 2011
The quantitative detection of total HER2 load by quantum dots and the identification of a new subtype of breast cancer with different 5-year prognosis.
Biomaterials
Chen C,Xia HS,Gong YP,Peng J,Peng CW,Hu MB,Zhu XB,Pang DW,Sun SR,Li Y
MA1-35720 was used in immunohistochemistry to evaluate a quantum dot-based nanotechnology for breast cancer prognosis
Mon Nov 01 00:00:00 UTC 2010
Trastuzumab induced in vivo tissue remodelling associated in vitro with inhibition of the active forms of AKT and PTEN and RhoB induction in an ovarian carcinoma model.
British journal of cancer
Delord JP,Quideau S,Rochaix P,Caselles O,Couderc B,Hennebelle I,Courbon F,Canal P,Allal BC
MA1-35720 was used in western blot to study the biological, molecular and cellular effects of Herceptin in ovarian carcinoma
Tue Jun 29 00:00:00 UTC 2010
Morphological and immunophenotypic features of primary and metastatic giant cell tumour of bone.
Virchows Archiv : an international journal of pathology
Alberghini M,Kliskey K,Krenacs T,Picci P,Kindblom L,Forsyth R,Athanasou NA
MA1-35720 was used in immunohistochemistry to study the relationship between bone tumors and lung nodules
Fri Jan 01 00:00:00 UTC 2010
Dendritic cell sarcomas/tumours of the breast: report of two cases.
Virchows Archiv : an international journal of pathology
Kapucuoglu N,Percinel S,Ventura T,Lang R,Al-Daraji W,Eusebi V
MA1-35720 was used in immunohistochemistry to report on two cases of dendritic cell sarcomas/tumours of the breast
Sun Mar 01 00:00:00 UTC 2009
Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers.
Human pathology
Liu H,Fan Q,Zhang Z,Li X,Yu H,Meng F
MA1-35720 was used in immunohistochemistry to study the prognostic features of basal-like breast tumors in a series of hormone receptor-negative invasive breast cancer tumors
Fri Feb 01 00:00:00 UTC 2008
Epidermal growth factor ligand/receptor loop and downstream signaling activation pattern in completely resected nonsmall cell lung cancer.
Cancer
Volante M,Saviozzi S,Rapa I,Ceppi P,Cappia S,Calogero R,Novello S,Borasio P,Papotti M,Scagliotti GV
MA1-35720 was used in immunohistochemistry to study EGF receptor pathway activation in completely resected non-small cell lung cancer
Sat Sep 15 00:00:00 UTC 2007
Expression of c-kit proto-oncogene product in breast cancer tissues.
Medical oncology (Northwood, London, England)
Eroğlu A,Sari A
MA1-35720 was used in immunohistochemistry to study the expression of the c-kit proto-oncogene protein in benign and malignant breast tumors
Thu Dec 20 00:00:00 UTC 2007
Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients.
International immunology
Oldford SA,Robb JD,Codner D,Gadag V,Watson PH,Drover S
MA1-35720 was used in immunohistochemistry to study the predictive value of tumor cell expression of HLA-DM in breast carcinoma patients
Wed Nov 01 00:00:00 UTC 2006
Prognostic and predictive value of c-erbB2 overexpression in osteogenic sarcoma.
Journal of cancer research and therapeutics
Rakesh Kumar V,Gupta N,Kakkar N,Sharma SC
MA1-35720 was used in immunohistochemistry to study the prognostic and predictive value of c-erbB2 overexpression in osteogenic sarcoma
Thu Dec 27 00:00:00 UTC 2007
Selective inhibition of HER2 inhibits AKT signal transduction and prolongs disease-free survival in a micrometastasis model of ovarian carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology
Delord JP,Allal C,Canal M,Mery E,Rochaix P,Hennebelle I,Pradines A,Chatelut E,Bugat R,Guichard S,Canal P
MA1-35720 was used in western blot to investigate the efficacy of trastuzumab in the prevention of relapse of ovarian carcinomas
Thu Dec 01 00:00:00 UTC 2005
Epidermal growth factor receptor (EGFR) expression in childhood brain tumors.
In vivo (Athens, Greece)
Bodey B,Kaiser HE,Siegel SE
MA1-35720 was used in immunocytochemistry to investigate the role of epidermal growth factor receptor (EGFR) expression in childhood brain tumors
Tue Oct 18 00:00:00 UTC 2005
Intraepidermal cells of Paget's carcinoma of the breast can be genetically different from those of the underlying carcinoma.
Human pathology
Morandi L,Pession A,Marucci GL,Foschini MP,Pruneri G,Viale G,Eusebi V
MA1-35720 was used in immunohistochemistry to study the genetic differences between intraepidermal cells of Paget's carcinoma and the underlying carcinoma
Mon Dec 01 00:00:00 UTC 2003
erbB-2 (HER-2) and breast cancer progression.
Applied immunohistochemistry & molecular morphology : AIMM
Edgerton SM,Moore D,Merkel D,Thor AD
MA1-35720 was used in immunohistochemistry to study HER2 expression in breast cancer primary tumors and metastases
Mon Sep 01 00:00:00 UTC 2003
Fine-needle aspiration cytology findings of an uncommon micropapillary variant of pure mucinous carcinoma of the breast: review of patients over an 8-year period.
Cancer
Ng WK
MA1-35720 was used in immunohistochemistry (paraffin) to discuss features used to classify pure mucinous carcinomas of the breast.
Fri Oct 25 00:00:00 UTC 2002
Toker cells are probably precursors of Paget cell carcinoma: a morphological and ultrastructural description.
Virchows Archiv : an international journal of pathology
Marucci G,Betts CM,Golouh R,Peterse JL,Foschini MP,Eusebi V
MA1-35720 was used in immunohistochemistry to study Toker cells as likely precursors of Paget cell carcinoma
Thu Aug 01 00:00:00 UTC 2002
Expression of erbB-4/HER-4 growth factor receptor isoforms in ovarian cancer.
Cancer research
Gilmour LM,Macleod KG,McCaig A,Gullick WJ,Smyth JF,Langdon SP
MA1-35720 was used in immunohistochemistry to investigate the expression of erbB-4/HER-4 GFR isoforms and its role in ovarian cancer
Thu Mar 01 00:00:00 UTC 2001
