Invitrogen

FABP4 Polyclonal Antibody

FABP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FABP4 Antibody (PA5-30591) in IHC (P)

FABP4 Polyclonal Antibody detects FABP4 protein at cytoplasm and nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse brown adipocyte. FABP4 stained by FABP4 Polyclonal Antibody (Product # PA5-30591) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

FABP4 Antibody in Immunocytochemistry (ICC/IF)

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产品信息

PA5-30591

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

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免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫细胞化学 (ICC/IF)

1:100-1:1,000

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产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to a region within amino acids 49 and 132 of Human FABP4

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.19 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2548065

产品详细信息

Recommended positive controls: 293T, A431, HeLa, HepG2.

Predicted reactivity: Rhesus Monkey (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

FABP4 belongs to the fatty acid binding protein (FABP) family. FABPs contribute to the transport of fatty acids and other lipids in various cellular pathways. FABP4 is expressed in adipocytes, macrophages, monocyte-derived dendritic cells, and myoepithelial cells. It delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Cryo-electron microscopy of adipose tissue extracellular vesicles in obesity and type 2 diabetes mellitus.

PloS one

Miroshnikova VV,Dracheva KV,Kamyshinsky RA,Yastremsky EV,Garaeva LA,Pobozheva IA,Landa SB,Anisimova KA,Balandov SG,Hamid ZM,Vasilevsky DI,Pchelina SN,Konevega AL,Shtam TA

PA5-30591 was used in Western Blot to characterize EVs secreted by visceral (VAT) and subcutaneous adipose tissue (SAT) of patients with obesity and T2DM with standard methods as well as analyze their morphology with cryo-electron microscopy.

Tue Feb 28 00:00:00 EST 2023

Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis.

Cell research

Wu J,Song D,Li Z,Guo B,Xiao Y,Liu W,Liang L,Feng C,Gao T,Chen Y,Li Y,Wang Z,Wen J,Yang S,Liu P,Wang L,Wang Y,Peng L,Stacey GN,Hu Z,Feng G,Li W,Huo Y,Jin R,Shyh-Chang N,Zhou Q,Wang L,Hu B,Dai H,Hao J

PA5-30591 was used in Immunocytochemistry-immunoflourescence to investigate the use of hESC-derived immunity-regulatory and matrix-regulatory cells in treating lung injury and fibrosis in mice.

Tue Sep 01 00:00:00 EDT 2020

A fully defined static suspension culture system for large-scale human embryonic stem cell production.

Cell death & disease

Li X,Ma R,Gu Q,Liang L,Wang L,Zhang Y,Wang X,Liu X,Li Z,Fang J,Wu J,Wang Y,Li W,Hu B,Wang L,Zhou Q,Hao J

Published figure using FABP4 polyclonal antibody (Product # PA5-30591) in Immunocytochemistry

Thu Aug 30 00:00:00 EDT 2018

In vitro osteoblastic differentiation of mesenchymal stem cells generates cell layers with distinct properties.

Stem cell research & therapy

Hanna H,Mir LM,Andre FM

PA5-30591 was used in Immunocytochemistry-immunoflourescence to study the role of miR-214 as an oncogene in human osteosarcoma.

Fri Jul 27 00:00:00 EDT 2018

Tube formation in the first trimester placental trophoblast cells: Differential effects of angiogenic growth factors and fatty acids.

Cell biology international

Pandya AD,Das MK,Sarkar A,Vilasagaram S,Basak S,Duttaroy AK

Published figure using FABP4 polyclonal antibody (Product # PA5-30591) in Western Blot

Wed Jun 01 00:00:00 EDT 2016

Heterogeneous Differentiation of Human Mesenchymal Stem Cells in 3D Extracellular Matrix Composites.

BioResearch open access

Jung JP,Bache-Wiig MK,Provenzano PP,Ogle BM

PA5-30591 was used in immunocytochemistry to analyze 3D extracellular matrix composites for heterogeneous differentiation of human mesenchymal stem cells

Wed Feb 10 00:00:00 EST 2016

Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation.

Molecular neurodegeneration

Caccamo A,Magrí A,Oddo S

Published figure using FABP4 polyclonal antibody (Product # PA5-30591) in Immunocytochemistry

Thu Nov 11 00:00:00 EST 2010

生物信息学

蛋白别名: 3T3-L1 lipid-binding protein; A-FABP; adipocyte fatty acid binding protein; Adipocyte lipid binding protein; Adipocyte lipid-binding protein; adipocyte protein aP2; Adipocyte-type fatty acid-binding protein; AFABP; ALBP; epididymis secretory protein Li 104; Fatty acid binding protein 4 adipocyte; fatty acid binding protein 4, adipocyte; Fatty acid-binding protein 4; Fatty acid-binding protein, adipocyte; HEL S 104; Myelin P2 protein homolog; P15; P2 adipocyte protein; Protein 422

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基因别名: 422/aP2; A-FABP; AFABP; ALBP; ALBP/Ap2; Ap2; FABP4; HEL-S-104; Lbpl

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UniProt ID: (Human) P15090, (Mouse) P04117

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Entrez Gene ID: (Human) 2167, (Mouse) 11770

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功能

transporter activity fatty acid binding lipid binding

参与通路