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FABP7 Antibody (MA5-47398) in IHC
Immunohistochemistry analysis of FABP7 in rat embryonic brain section. Samples were stained with FABP7 monoclonal antibody (Product # MA5-47398) using a dilution of 1:500 (green). Costained with chicken pAb to vimentin dilution 1:5,000 in red. FABP7 antibody stains developing astrocytes and radial glia, while vimentin antibody reveals cytoplasmic intermediate filaments. Since the sub cellular distribution of these two proteins is distinct their expression patterns overlap but are not identical.
产品信息
MA5-47398
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2A84
抗原
Recombinant full length human FABP7 expressed in and purified from E. coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS with 50% glycerol
内含物
5mM sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2942380
靶标信息
FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B FABP; B-FABP; BLBP; brain lipid binding protein; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; hypothetical protein DKFZp547J2313; Mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; OTTHUMP00000017119; RP11-548E19.1
基因别名: B-FABP; BFABP; BLBP; FABP7; FABPB; MRG
UniProt ID: (Human) O15540, (Rat) P55051, (Mouse) P51880
Entrez Gene ID: (Human) 2173, (Rat) 80841, (Mouse) 12140
