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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. FANCG is the protein for complementation group G.
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蛋白别名: DNA repair protein XRCC9; Fanconi anemia group G protein; Fanconi anemia group G protein homolog; Fanconi anemia, complementation group G; Protein FACG; truncated Fanconi anemia group G protein; X-ray repair complementing defective repair in Chinese hamster cells 9; X-ray repair, complementing defective, in Chinese hamster, 9
基因别名: AU041407; FAG; FANCG; XRCC9
UniProt ID: (Human) O15287, (Mouse) Q9EQR6
Entrez Gene ID: (Human) 2189, (Rat) 691105, (Mouse) 60534