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Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Fatty acid synthase; MGC14367; MGC15706; short chain dehydrogenase/reductase family 27X, member 1; Type I FAS; Type I Fatty Acid Synthase
基因别名: A630082H08Rik; FAS; FASN; OA-519; SDR27X1
UniProt ID: (Human) P49327, (Mouse) P19096, (Rat) P12785
Entrez Gene ID: (Human) 2194, (Mouse) 14104, (Rat) 50671