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Product may be used with Western Blot (Cell lysate).
Immunogen sequence: VTCARCIGDE SFALGSQNEV YCLDDFYRKF APVCSICENP IIPRDGKDAF KIECMGRNFH ENCYRCEDCR ILLSVEPTDQ GCYPLNNHLF CKPCHVKRSA AGCC
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CSX-associated LIM; FBLP-1; Filamin-binding LIM protein 1; filamin-binding LIM protein-1; MIG2-interacting protein; Migfilin; mitogen-inducible 2 interacting protein; Mitogen-inducible 2-interacting protein
基因别名: CAL; FBLIM1; FBLP-1; FBLP1
UniProt ID: (Human) Q8WUP2
Entrez Gene ID: (Human) 54751
分子生物学功能: kinase modulator