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产品信息
20910-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FGD5 Fusion Protein Ag15037 (923-1262 aa encoded by BC035364)
偶联物
Unconjugated
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MRALDDMDH EGRDTLAREE LRQGLSELPA IHDLHQGILE ELEERLSNWE SQQKVADVFL AREQGFDHHA THILQFDRYL GLLSENCLHS PRLAAAVREF EQSVQGGSQT AKHRLLRVVQ RLFQYQVLLT DYLNNLCPDS AEYDNTQGAL SLISKVTDRA NDSMEQGENL QKLVHIEHSV RGQGDLLQPG REFLKEGTLM KVTGKNRRPR HLFLMNDVLL YTYPQKDGKY RLKNTLAVAN MKVSRPVMEK VPYALKIETS ESCLMLSASS CAERDEWYGC LSRALPEDYK AQALAAFHHS VEIRERLGVS LGERPPTLVP VTHVMMCMNC GCDFSLTLRR H (923-1262 aa encoded by BC035364)
靶标信息
FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FYVE, RhoGEF and PH domain-containing protein 5; Zinc finger FYVE domain-containing protein 23
基因别名: FGD5; ZFYVE23
UniProt ID: (Human) Q6ZNL6
Entrez Gene ID: (Human) 152273
