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FGF13 Antibody (CF807774) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGF13 (RC204164, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FGF13. Positive lysates LY418207 (100 µg) and LC418207 (20 µg) can be purchased separately from OriGene.
产品信息
CF807774
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1D5
抗原
Full length human recombinant protein of human FGF13 produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AFGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF-13; FGF13A; FGFA; FHF-2; Fibroblast growth factor; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1
基因别名: FGF-13; FGF13; FGF2; FHF-2; FHF2
UniProt ID: (Human) Q92913
Entrez Gene ID: (Human) 2258
MAPK cascade
neuron migration
negative regulation of microtubule depolymerization
signal transduction
cell-cell signaling
nervous system development
learning
memory
hippocampus development
cerebral cortex cell migration
activation of protein kinase activity
establishment of neuroblast polarity
microtubule polymerization
negative regulation of collateral sprouting
protein localization to plasma membrane
