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产品信息
CF502788
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI9E5
抗原
Human recombinant protein fragment corresponding to amino acids 29-209 of human FGF21 produced in HEK293T cell.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FGF; FGF-21; FGFL; Fibroblast growth factor; Fibroblast growth factor 21; PRO10196
基因别名: FGF21; UNQ3115/PRO10196
UniProt ID: (Human) Q9NSA1
Entrez Gene ID: (Human) 26291
signal transduction
cell-cell signaling
positive regulation of cell proliferation
regulation of low-density lipoprotein particle clearance
response to activity
endoplasmic reticulum unfolded protein response
response to nutrient levels
cellular response to drug
positive regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of glucose import
positive regulation of ERK1 and ERK2 cascade
cellular response to glucose stimulus
cellular response to low-density lipoprotein particle stimulus
endothelial cell apoptotic process
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
negative regulation of endothelial cell apoptotic process
