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FGF8 Antibody (PA5-47598) in IHC (P)
Immunohistochemical analysis of FGF8 in immersion fixed paraffin-embedded sections of human prostate. Samples were incubated in FGF8 polyclonal antibody (Product # PA5-47598) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to epithelial and endothelial... View More
产品信息
PA5-47598
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse FGF-8b Gln23-Arg215
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2608867
产品详细信息
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-4, rhFGF-5, rhFGF-6, rhFGF-7 and rhFGF-9 is observed. This antibody will cross-react with recombinant mouse FGF-8c in neutralizing bioassay.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIGF; androgen-induced; Androgen-induced growth factor; FGF; FGF-8; Fibroblast growth factor; Fibroblast growth factor 8; HBGF-8; Heparin-binding growth factor 8; MGC149376
基因别名: Aigf; Fgf-8; Fgf8
UniProt ID: (Mouse) P37237
Entrez Gene ID: (Mouse) 14179
MAPK cascade
patterning of blood vessels
branching involved in ureteric bud morphogenesis
organ induction
kidney development
neural plate morphogenesis
heart looping
blood vessel remodeling
heart morphogenesis
outflow tract septum morphogenesis
outflow tract morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
apoptotic process
response to oxidative stress
multicellular organism development
determination of left/right symmetry
heart development
motor neuron axon guidance
mesodermal cell migration
positive regulation of cell proliferation
gonad development
fibroblast growth factor receptor signaling pathway
embryo development ending in birth or egg hatching
positive regulation of gene expression
telencephalon development
pallium development
subpallium development
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
forebrain neuron development
central nervous system neuron development
signal transduction involved in regulation of gene expression
cell differentiation
lung development
BMP signaling pathway
male genitalia development
thyroid gland development
otic vesicle formation
midbrain-hindbrain boundary development
dorsal/ventral axon guidance
embryonic heart tube development
limb morphogenesis
embryonic hindlimb morphogenesis
aorta morphogenesis
inner ear morphogenesis
regulation of odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell fate commitment
positive regulation of mitotic nuclear division
positive regulation of organ growth
generation of neurons
forebrain morphogenesis
positive chemotaxis
positive regulation of cell division
negative regulation of cardiac muscle tissue development
pharyngeal system development
canonical Wnt signaling pathway
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
bone development
lung morphogenesis
branching involved in salivary gland morphogenesis
neuroepithelial cell differentiation
dopaminergic neuron differentiation
cell migration involved in mesendoderm migration
