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Application
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FGL2 Antibody (PA5-36390) in WB
Western blot analysis of FGL2 in Lane 1: CT26 whole cell lysate (40 µg), Lane 2: SP2/0 whole cell lysate (40 µg), Lane 3: C6 whole cell lysate (40 µg), Lane 4: A549 whole cell lysate (40 µg), Lane 5: HeLa whole cell lysate (40 µg). Samples were incubated with FGL2 polyclonal antibody (Product # PA5-36390) at a dilution of 1:500.
产品信息
PA5-36390
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 6-60 of human Fgl2
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553501
产品详细信息
This antibody detects endogenous protein at a molecular weight of 50 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: associated with MHV-3 induced prothrombinase activity; Cytotoxic T-lymphocyte-specific protein; fibrinogen-like 2; Fibrinogen-like protein 2; Fibroleukin; Prothrombinase; pT49
基因别名: AI385601; FGL2; Fiblp; musfiblp; pT49; T49
UniProt ID: (Human) Q14314, (Mouse) P12804
Entrez Gene ID: (Human) 10875, (Mouse) 14190, (Rat) 84586
