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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 200 kDa FAK family kinase-interacting protein; FAK family kinase-interacting protein of 200 kDa; FIP200; phosphatase 1, regulatory subunit 131; RB1-inducible coiled-coil 1; RB1-inducible coiled-coil protein 1
基因别名: ATG17; CC1; FIP200; KIAA0203; PPP1R131; RB1CC1; RBICC
UniProt ID: (Human) Q8TDY2
Entrez Gene ID: (Human) 9821
分子生物学功能:
scaffold/adaptor protein