Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-51470
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641655
产品详细信息
Immunogen sequence: LPKKDIIKFL QEHGSDSFLA EHKLLGNIKN VAKTANKDHL VTAYNHLFET KRFKGTESIS KVSEQVKNVK LNEDKPKETK SEETLDEGPP KYTKSVLKKG DKTNFPKKGD VVHCWYTGTL QDGT
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.
靶标信息
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 25 kDa FK506-binding protein; 25 kDa FKBP; FK506 binding protein 3, 25kDa; FK506-binding protein 25, T-cell; FK506-binding protein 3; FK506-binding protein 3 (25kD); FKBP-25; FKBP-3; Immunophilin FKBP25; Peptidyl-prolyl cis-trans isomerase FKBP3; PPIase FKBP3; rapamycin binding protein; Rapamycin-selective 25 kDa immunophilin; Rotamase
基因别名: 25kDa; FKBP-25; FKBP-3; FKBP25; FKBP3; PPIase
UniProt ID: (Human) Q00688, (Mouse) Q62446
Entrez Gene ID: (Human) 2287, (Mouse) 30795, (Rat) 299104
