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Additional Information: This antibody is expected to recognize both reported isoforms (NP_001620.2; NP_001191335.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein
基因别名: ALOX5AP; FLAP
UniProt ID: (Human) P20292
Entrez Gene ID: (Human) 241
分子生物学功能: transferase