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Immunogen sequence: ELDMSDFEE QFKTKSQGPS LDLSALKSKA AQKAPSKATL IEANRAKNLA ITLRKGNLGA ERICQAIEAY DLQALGLDFL ELLMRFLPTE YERSLITRFE REQRPMEELS EEDRFMLCFS RIPRLPERMT TLTFLGNFPD TAQLLMPQLN AIIAASMSIK SSDKLRQILE IVLAFGNYMN SSKRGAAYGF RLQSLDALLE MKSTDRKQTL LHYLVKVIAE KYPQLTGFHS DLHFLDKAGS VSLDSVLADV RSLQRGLELT QREFVRQDDC MVLKEFLRAN SPTMDKLLAD SKTAQEAFES VVEYFGENPK TTSP (39-351 aa encoded by BC001710)
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; Leukocyte formin
基因别名: C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; FRL1; KW-13
UniProt ID: (Human) O95466
Entrez Gene ID: (Human) 752