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Application
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FOXP4 Antibody (16772-1-AP) in ICC/IF
Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using (Product # 16772-1-AP) (FOXP4 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).
产品信息
16772-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FOXP4 Fusion Protein Ag10047 (327-678 aa encoded by BC052803)
偶联物
Unconjugated
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: NTEHALDDR STAQCRVQMQ VVQQLEIQLA KESERLQAMM AHLHMRPSEP KPFSQPLNPV PGSSSFSKVT VSAADSFPDG LVHPPTSAAA PVTPLRPPGL GSASLHGGGP ARRRSSDKFC SPISSELAQN HEFYKNADVR PPFTYASLIR QAILETPDRQ LTLNEIYNWF TRMFAYFRRN TATWKNAVRH NLSLHKCFVR VENVKGAVWT VDEREYQKRR PPKMTGSPTL VKNMISGLSY GALNASYQAA LAESSFPLLN SPGMLNPGSA SSLLPLSHDD VGAPVEPLPS NGSSSPPRLS PPQYSHQVQV KEEPAEAEED RQPGPPLGAP NPSASGPPED RDLEEELPGE ELS (327-678 aa encoded by BC052803)
靶标信息
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ40908; FLJ44184; fork head-related protein like A; Fork head-related protein-like A; Forkhead box protein P4; foxp4; mFKHLA; OTTHUMP00000043536; winged-helix repressor FOXP4
基因别名: 1200010K03Rik; 2310007G05Rik; FKHLA; FOXP4; hFKHLA; mFKHLA
UniProt ID: (Human) Q8IVH2, (Mouse) Q9DBY0
Entrez Gene ID: (Human) 116113, (Mouse) 74123, (Rat) 363185
RNA polymerase II transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
metal ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
protein heterodimerization activity
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
heart development
embryonic foregut morphogenesis
lung secretory cell differentiation
regulation of lung goblet cell differentiation
negative regulation of lung goblet cell differentiation
regulation of transcription from RNA polymerase II promoter
