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FPR2/ALX (extracellular) Antibody (AFR-002-200UL) in WB
Western blot analysis of Human HL-60 promyelocytic leukemia (lanes 1 and 3) and K562 chronic myelogenous leukemia (lanes 2 and 4) cell lysates: - 1,2. Anti-Human FPR2/ALX (extracellular) Antibody (#AFR-002), (1:200).3,4. Anti-Human FPR2/ALX (extracellular) Antibody , preincubated with Human FPR2/ALX (extracellular) Blocking Peptide (#BLP-FR002).
产品信息
AFR-002-200UL
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)GGTPEERLKVAIT, corresponding to amino acid residues 184-196 of human FPR2/ALX, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FMLP-R-I; FMLP-related receptor I; fMLPR1; Formyl peptide receptor-like 1; FPR-like 1; Fpr-rs1; Fprl-1; HM63; Lipoxin A4 receptor; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin receptor; LXA4 receptor; N-formyl peptide receptor 2; RFP
基因别名: ALXR; FMLP-R-II; FMLPX; FPR2; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
UniProt ID: (Human) P25090
Entrez Gene ID: (Human) 2358
