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产品信息
PA5-49805
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from internal of human FRK.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2635258
产品详细信息
The antibody detects endogenous levels of total FRK protein.
靶标信息
FRK (PTK5) is a nuclear protein and may function during G1 and S phase of the cell cycle, suppressing growth. The human FRK gene maps to chromosome 6q21-q22.3 and encodes a 505 amino acid protein. The protein belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell src-homology tyrosine kinase; Beta-cell Src-homology tyrosine kinase; BSK; EC 2.7.1.112; EC 2.7.10.2; FYN-related kinase; fyn-related Src family tyrosine kinase; GASK; Gastrointestinal-associated kinase; Gastrointestinal-associated tyrosine kinase; GTK; Intestine tyrosine kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5; PTK5 protein tyrosine kinase 5; src related tyrosine kinase; Tyrosine-protein kinase FRK
基因别名: BSK; BSK/IYK; C85044; FRK; Gask; GTK; Iyk; PTK5; RAK
UniProt ID: (Human) P42685, (Mouse) Q922K9, (Rat) Q62662
Entrez Gene ID: (Human) 2444, (Mouse) 14302, (Rat) 79209
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
actin cytoskeleton organization
cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
negative regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
