Invitrogen

FUCA2 Polyclonal Antibody

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FUCA2 Antibody (PA5-70565) in WB

Western blot analysis of FUCA2 on mouse heart tissue lysate. The sample was probed with a FUCA2 polyclonal antibody (Product # PA5-70565) using a primary antibody dilution of 1.0 µg/mL.

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产品信息

PA5-70565

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1.0 µg/mL

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产品规格

种属反应

Mouse

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

synthetic peptide directed towards the middle region of mouse FUCA2

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2689942

产品详细信息

This target displays homology in the following species: Cow: 92%; Dog: 77%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 92%

靶标信息

FUCA2 (Alpha-L-fucosidase) catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model.

Frontiers in genetics

Song Z,Xu Y,Zhang L,Zhou L,Zhang Y,Han Y,Li X,Yu P,Qu Y,Zhao W,Qin C

PA5-70565 was used in Western Blotting to demonstrate that some urinary exosome proteins, especially Annexin 2 and Clusterin, as nanometer-sized particles, enable detection of differences before amyloid-β-plaque deposition in 5XFAD mouse model, which may present an ideal non-invasive source of biomarkers for prevention of AD.