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FYCO1 Antibody (PA5-104495) in IHC (P)
Immunohistochemistry analysis of FYCO1 in rat heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with FYCO1 polyclonal antibody (Product # PA5-104495) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-104495
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FYCO1(Accession Q9BQS8), corresponding to amino acid residues E832-C882.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853796
产品详细信息
Antibody detects endogenous levels of total FYCO1.
靶标信息
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp779K1152; FLJ13335; FYVE and coiled-coil domain-containing protein 1; MGC126517; MGC126519; RUN and FYVE domain containing 3; Zinc finger FYVE domain-containing protein 7
基因别名: CATC2; CTRCT18; FYCO1; RUFY3; ZFYVE7
UniProt ID: (Human) Q9BQS8
Entrez Gene ID: (Human) 79443, (Rat) 301085
