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产品信息
PA5-23159
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acid 150-200 of human Frizzled-10
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
whole serum with 50% glycerol
内含物
0.025% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2540685
靶标信息
FZD10/Frizzled-10 is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family and containing a signal peptide, a cysteine-rich domain in the N-terminal, seven transmembrane domains and a C-terminal PDZ domain-binding motif. It is involved in transduction, intercellular transmission of polarity information during tissue morphogenesis in differentiated tissues and as a receptor for Wnt proteins. FZD10 is expressed highly in placenta, fetal kidney, fetal lung, brain cerebellum, cerebral cortex, medulla and spinal cord with very low levels in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung and skeletal muscle.
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生物信息学
蛋白别名: CD350; CD350 antigen; frizzled 10, seven transmembrane spanning receptor; frizzled family receptor 10; frizzled homolog 10; Frizzled-10; Fz-10; FzE7
基因别名: CD350; FZ-10; Fz10; FZD10; FzE7; hFz10
UniProt ID: (Human) Q9ULW2, (Mouse) Q8BKG4
Entrez Gene ID: (Human) 11211, (Mouse) 93897
G-protein coupled receptor signaling pathway
neuron differentiation
regulation of actin cytoskeleton organization
negative regulation of GTPase activity
non-canonical Wnt signaling pathway via JNK cascade
positive regulation of JUN kinase activity
positive regulation of GTPase activity
canonical Wnt signaling pathway
cellular response to retinoic acid
signal transduction
cell surface receptor signaling pathway
multicellular organism development
Wnt signaling pathway
non-canonical Wnt signaling pathway
