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Invitrogen
FZD7 Monoclonal Antibody (151143)
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FZD7 Antibody (MA5-24378) in ICC/IF
Immunocytochemistry analysis of FZD7 in immersion fixed HEK293 human embryonic kidney cell line. Samples were incubated in FZD7 monoclonal antibody (Product # MA5-24378) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to the cell surface.
产品信息
MA5-24378
产品规格
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
151143
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-7 Gln33-Leu185
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, no cross-reactivity with recombinant mouse Frizzled-1, -3, -4 or -8 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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