Search Thermo Fisher Scientific
MA1-43001 detects Factor V in human samples.
MA1-43001 has successfully been used in RIA and Western blot applications.
MA1-43001 was derived from the 120kD activation peptide of human factor V.
Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activated protein C cofactor; Coagulation factor V; coagulation factor V (proaccelerin, labile factor); coagulation factor V jinjiang A2 domain; Factor 5; factor V Leiden; Factor5; Proaccelerin, labile factor
基因别名: F5; FVL; PCCF; RPRGL1; THPH2
UniProt ID: (Human) Q8WWQ6
Entrez Gene ID: (Human) 2153