Invitrogen

Factor XI Polyclonal Antibody

产品信息

PA1-43048

应用

建议稀释比

已发表文章

免疫印迹 (WB)

25 µg/mL

酶联免疫吸附实验 (ELISA)

5-10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Sheep / IgG

分类

Polyclonal

类型

Antibody

抗原

Human Factor XI.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

12.4 mg/mL

纯化类型

Ammonium sulfate precipitation, Ion-exchange chromatography

保存液

50% water with 50% glycerol

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_1074350

产品详细信息

PA1-43048 detects Factor XI in human samples.

PA1-43048 has successfully been used in Western blot and ELISA applications.

PA1-43048 was derived from human factor XI.

靶标信息

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

仅用于科研。不用于诊断过程。未经明确授权不得转售。