Proteintech

Fibrinogen beta chain Monoclonal Antibody (1F8E4)

Fibrinogen beta chain Antibody in Western Blot (WB)

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Fibrinogen beta chain Antibody (66186-1-IG) in WB

Fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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产品信息

66186-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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产品规格

种属反应

Human

已发表种属

Not Applicable

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

1F8E4

抗原

Fibrinogen beta chain Fusion Protein Ag10205 (142-491 aa encoded by BC107766)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.45 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: SSSFQYMYL LKDLWQKRQK QVKDNENVVN EYSSELEKHQ LYIDETVNSN IPTNLRVLRS ILENLRSKIQ KLESDVSAQM EYCRTPCTVS CNIPVVSGKE CEEITRKGGE TSEMYLIQPD SSVKPYRVYC DMNTENGGWT VIQNRQDGSV DFGRKWDPYK QGFGNVATNT DGKNYCGLPG EYWLGNDKIS QLTRMGPTEL LIEMEDWKGD KVKAHYGGFT VQNEANKYQI SVNKYRGTAG NALMDGASQL MGENRTMTIH NGMFFSTYDR DNDGWLTSDP RKQCSKEDGG GWWYNRCHAA NPNGRYYWGG QYTWDMAKHG TDDGVVWMNW KGSWYSMRKM SMKIRPFFPQ Q (142-491 aa encoded by BC107766)

靶标信息

FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

仅用于科研。不用于诊断过程。未经明确授权不得转售。