Invitrogen

Fibulin 1 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他12个Fibulin 1抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (6)
高级验证 (1)

Fibulin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Fibulin 1 Antibody (PA5-51612) in IHC (P)

Immunohistochemical analysis of Fibulin 1 in human lymph node using Fibulin 1 Polyclonal Antibody (Product # PA5-51612) shows very weak cytoplasmic positivity in non-germinal center cells.

Fibulin 1 Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-51612

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:500-1:1000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human Fibulin 1. Recombinant protein control fragment (Product #RP-100521).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2641630

产品详细信息

Immunogen sequence: CESGIHNCLP DFICQNTLGS FRCRPKLQCK SGFIQDALGN CIDINECLSI SAPCPIGHTC INTEGSYTCQ KNVPNCGRGY HLNEEGTRCV DVDECAPPAE PCGKGHRCVN SPGSFRCECK TGYYFDGISR MCVDVNE

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

靶标信息

Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes and blood. Fibulin-1 self associates as well as binds to calcium, fibronectin, laminin, nidogen and fibrinogen. These interactions, individually or in combination, may account for the observed association of Fibulin-1 with basement membranes, connective tissue, elastic fibers and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies point to the inhibition of cancer cell motility with increasing exposure to Fibulin-1. The exact function of Fibulin-1 in the cell is unknown.

仅用于科研。不用于诊断过程。未经明确授权不得转售。