Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
BS-10287R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human GADD34, amino acids 401-500.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Growth arrest and DNA damage-inducible protein GADD34; growth arrest and DNA-damage-inducible 34; myeloid differentiation primary response gene 116; Myeloid differentiation primary response protein MyD116; Myeloid differentiation primary response protein MyD116 homolog; PEG-3; PR15A; Progression elevated gene 3 protein; Protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1, regulatory subunit 15A
基因别名: 9630030H21; GADD34; Myd116; Peg-3; Peg3; PPP1R15A; RGD1624209
UniProt ID: (Human) O75807, (Mouse) P17564, (Rat) Q6IN02
Entrez Gene ID: (Human) 23645, (Mouse) 17872, (Rat) 171071
regulation of translation
apoptotic process
positive regulation of gene expression
endoplasmic reticulum unfolded protein response
negative regulation of phosphoprotein phosphatase activity
positive regulation of phosphoprotein phosphatase activity
positive regulation of peptidyl-serine phosphorylation
response to endoplasmic reticulum stress
negative regulation of protein dephosphorylation
regulation of translational initiation by eIF2 alpha dephosphorylation
positive regulation of transcription from RNA polymerase I promoter
regulation of catalytic activity
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
peptidyl-serine dephosphorylation
protein localization to endoplasmic reticulum
positive regulation of peptidyl-serine dephosphorylation
negative regulation of response to endoplasmic reticulum stress
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of protein phosphorylation
cellular response to DNA damage stimulus
cell cycle arrest
aging
negative regulation of cell proliferation
negative regulation of peptidyl-threonine phosphorylation
negative regulation of protein processing
positive regulation of translational initiation in response to stress
cellular response to UV
cellular response to drug
response to immobilization stress
response to cocaine
positive regulation of apoptotic process
regulation of angiogenesis
negative regulation of cell death
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to antibiotic
cellular response to carbohydrate stimulus
cellular response to methyl methanesulfonate
cellular response to calcium ion starvation
response to environmental enrichment
cellular response to oxygen-glucose deprivation
negative regulation of PERK-mediated unfolded protein response
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
cellular response to desipramine
cellular response to cordycepin
cellular response to gold(3+)
cellular response to methamphetamine hydrochloride
